The Genetic Basis of Sleep and Sleep DisordersPaul Shaw, Mehdi Tafti, Michael J. Thorpy Cambridge University Press, 2013. okt. 24. - 399 oldal The first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists. |
Más kiadások - Összes megtekintése
The Genetic Basis of Sleep and Sleep Disorders Paul Shaw,Mehdi Tafti,Michael J. Thorpy Korlátozott előnézet - 2013 |
Gyakori szavak és kifejezések
Acad Sci USA activity adenosine allele analysis behavioral Biol BMAL1 brain candidate gene cataplexy cells chromosome circadian clock circadian rhythms clock genes cognitive complex cortex decreased disease diurnal preference Drosophila effects elegans epigenetic factors FASP flies function gene expression genome genome-wide association studies genotype GWAS haplotype Hcrt heritability homeostasis homeostatic human hypersomnia hypocretin identified impairments increased individuals insomnia levels linkage loci locus mapping markers mechanisms melatonin memory consolidation metabolic mice molecular mouse mutation narcolepsy Nat Genet Natl Acad Sci neurons Neurosci NREM obstructive sleep apnea onset orexin orexin neurons pathways patients PER2 PER3 PGD2 phenotype Physiol polymorphism population Proc Natl Acad protein psychiatric rats receptor region REM sleep restless legs syndrome role sleep and wakefulness sleep deprivation sleep disorders sleep homeostasis sleep loss sleep phase sleep regulation Sleep Res SNPs synaptic traits transcription twins variants zebrafish