Fluid; the villous Coat was very generally inflamed, and several of the Ruga were livid, and of a Chocolate Colour; there were a great Number of mortified Spots, some like flattened black Currants; others more raised like Pustules; and in Places, the villous Coat was ulcerated and destroyed. No other Parts exhibited any morbid Look. The STOMACH of this Animal, presented such determined Marks of Disease, that a Drawing was taken, and a PLATE is subjoined, to illustrate these Appearances. As I wished to prove, if possible, whether the Fluid contained in these apparent Pustules, had the Power of infecting other Animals, I inoculated two Rabbits with it, in several Places, but without producing the Disease, or affecting the Health of the Animals, apparently in the slightest Degree."

Among the Methods, which seem to promise and present, a well-grounded Expectancy, for the Prevention of this dreadful Disorder, we shall recite Mr. G.'s Remarks as to EXTIRPATION and ABLUTION.

"Much Caution and Judgment is requisite, in Excising the bitten Part. I have known of Failures, where the Parts were excised, and afterwards cauterized; but I am fully persuaded, that this arises from Want of sufficient Attention, to some of the minuter Circumstances of the Operation.

"The first thing requisite, before the Excision of the bitten part, is to wash, not only the Inside of the Wound, but also the surrounding Parts, with great Care; for, if this be neglected, and the poisonous Saliva be not removed, in making the Incisions on each Side of the Wound, the sound Portions through which they are made, will be inoculated with the VIRUS. Two Incisions should then be made, one on each Side of the Wound, forming an Ellipsis in those that will admit of it, which should be carried to such a Depth, as completely to remove the Part. It should then be carefully examined, if there is any Part in the Piece excised, through which, the Dog's TooтH appears to have passed; and in case there is, the Excision should be carried deeper. In making the Incisions, great Attention should be paid, to the Direction of the TooтH; and, if the Knife should enter the Wound, made by the Doc's TOOTH, I should consider it always necessary to recommence the Operation, with a CLEAN KNIFE, and this, as often, as the Occurrence should take place: for, if we continue to use the same Knife, which is likely to be contaminated, in consequence of its entering the wounded Parts, the Operation may be rendered useless, by the sound Parts becoming inoculated with the CANINE VIRUS *.

* I have, says Mr. G. in two Instances, lately rubbed Indian Ink mixed with a little Vola

"For the Purposes of ABLUTION, at, and after Excision, I generally employ the Volatile Alkali with Water, for the following Reasons:-That of the different Alkalies, the Volatile, gives a greater Fluidity to the Saliva, and at the same time, completely dissolves it. Besides it possesses another Advantage, it may be used without much Pain to the Patient, from its being a less powerful Caustic. Some Attention also is necessary, even in the Cleaning of the Parts, from the morbid Saliva. There is another Circumstance, of too much Importance to pass unnoticed, that is, the Employing frequently clean Sponges during the Operation: perhaps fresh Lint will often answer the Purpose, and may prevent the Risk of using the Sponge, which may have been contaminated with the VIRUS. The Wounds after EXTIRPATION, should then be again freely washed, with a weak Solution of Volatile Alkali, and dressed with simple Dressing, or may be drawn together, with adhesive Plaster.

"A Variety of Writers, have recommended strongly, the keeping open the Wound by stimulating Applications, for some length of Time, but when the Whole of the Parts have been removed (which ought to be done without leaving the smallest Portion behind), I cannot see, what Good can arise from so doing. There are, however, many Parts of the Body, very unfavourable to EXTIRPATION, or where it cannot possibly be performed. In such cases, where they cannot be excised with Safety, the Operation, except the mere Removal of the ragged Parts, should not be attempted; and other Means should therefore be resorted to; and the next perhaps most efficacious Remedy, is ABLUTION. For this Purpose, I recommend a weak Solution of the Volatile Alkali, viz. of Water four parts, of Volatile Alkali one part. When stronger Solutions are employed, the more solid Parts become corroded, and the corroding Liquor, is very likely to hold the VIRUS in Solution. With the above, as it is fully capable of dissolving the Saliva, the wounded Parts should first be freely washed, and Injections with a Syringe, be forcibly made into the Wound; which should be persevered in, for a considerable Duration: after this, warm Water may be used, in place of the Solution, in order to promote a flow of Blood, by which means, any Portion that might possibly remain, will be washed out. By ABLUTIONS assiduously employed, (and by the Aid of a Syringe, the Fluids, may be directed with great Force, into the Wound,) it is to be hoped the Patient will be completely freed, from the canine VIRUS, and consequently from the Danger, which usually follows, when such Precautions are neglected.

"Perhaps among the most popular REMEDIES, none can be more appropriate, than that recommended, by the late celebrated Dr. PERCIVAL. He advised all Persons, the

tile Alkali, (Aq. Ammon. pur.) into the bitten Parts, so as to completely black the Inside of the Wound, which has been a considerable Guide to Me, in performing the OPERATION.

Moment they received the Bite of a rabid Animal, to apply to the first SPRING, BROOK, POOL, or DITCH; and as WATER is generally within our Reach, the WOUND may be easily cleansed. This he urged, to be diligently persevered in, till a SURGEON arrived, to excise the Parts.

"It has been observed, that there is always a peculiar SENSATION in the PARTS which have been bitten, PRECEDING the Accession of the Disease; therefore there is every Reason to hope, that the Removal of the Part, may be of Use even after a considerable Interval, and consequently, it always, if possible, should be done. In the Determination of the Question, as to the precise Time, when EXTIRPATION of the PARTS infected by the Bite, may be performed; it is of great Importance to consider, whether the Poison does not always remain in the Substance, where it is first diffused, until by Inflammation, or by some other Cause, a sufficient Dose is generated, to infect the WHOLE SYSTEM. Indeed the notorious Connexion, between a painful or inflamed State of the original Wound, immediately preceding the constitutional Symptoms, warrants this Supposition, and points out the Expediency, of removing or destroying the Parts to the last, although the Symptoms of HYDROPHOBIA should have commenced. That different Substances, do remain insoluble in the cellular Substance, for a considerable length of Time, even during the Life of an Individual, is sufficiently exemplified, in different Persons that have been tattowed, in Consequence of which, the colouring Matter, as Charcoal, Vermilion, or Indian Ink, which has been employed, always remains conspicuous under the SKIN, and as the canine VIRUS may be considered as a Fluid, or nearly so,—if it lodges in the cellular Substance of the PART wounded, until it accumulates in sufficient Quantity, to poison the WHOLE FRAME, it may be expected to diffuse itself gradually, to a greater Extent, in Proportion to the Distance of Time from the Bite; and hence every Excision should embrace, a large Portion of the surrounding PARTS, when the PERIOD, from the Infliction of the Wound, is much protracted."

The Whole of this DISSERTATION, and the annexed Case from Mr. CARLYLE, exhibit strong, and curious, Discrimination, and is a most valuable Addition towards the Prevention, and for the Treatment of this terrific, and at PRESENT, almost universally, FATAL DISEASE.

Worming Dogs.

So much in RECOMMENDATION of the Worming of Dogs, was said in a former Volume, that there would be no Need to resume the Subject, had not the Details of Cases,