Melatonin: From Molecules to TherapyNova Publishers, 2007 - 906 Seiten Melatonin is a neurohormone produced in the brain by the pineal gland, from the amino acid tryptophan. Melatonin possesses antioxidant activity, and many of its proposed therapeutic or preventive uses are based on this property. This book presents a wide spectrum of research on melatonin. |
Inhalt
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Neural Regulation of Melatonin Synthesis | 81 |
Regulation of Melatonin Synthesis Animal versus Human Studies | 117 |
Toward a Chronome Time Structure of Melatonin | 135 |
Section II Therapeutic Perspectives | 481 |
Pineal Region Tumors | 483 |
Melatonin and Cancer | 499 |
Therapeutic Perspectives of Gastrointestinal Melatonin | 529 |
Endogenous Versus Exogenous Effects of Melatonin | 547 |
Melatonin Circadian Rhythms in Women with Depression Relationship to the Reproductive Cycle | 571 |
Melatonin Therapy of Circadian Rhythm Sleep Disorders in Neurodevelopmentally Disordered Children A Neurological Viewpoint | 581 |
Treatment by Melatonin of a Genetic Disorder SmithMagenis Syndrome | 605 |
Chronobiological Aspects of Melatonin Activity | 177 |
The Molecular Basis to the Circadian Effects of Melatonin | 197 |
Melatonin Effects on Uterine Physiology | 207 |
Melatonin and Human Reproduction Why the Effect is so Elusive? | 219 |
Melatonin Immunomodulatory Signal | 227 |
Photoperiodic vs NonPhotoperiodic Animals Circadian and Seasonal Changes in Immunity | 247 |
Melatonin An Endogenous Antiestrogen with Oncostatic Properties | 261 |
Melatonin and Cancer Basic Research | 273 |
Melatonin in Retinal Pathophysiology | 283 |
The Physiology Pharmacology and Anatomical Distribution of Melatonin Receptors in Visual System Nuclei in the Vertebrate CNS | 295 |
Antioxidant Capacity of the Neurohormone Melatonin | 317 |
Protective Role of Melatonin against Mitochondrial Damage in Inflammation | 327 |
Protective Effects of Melatonin against Hyperhomocysteinemia | 349 |
Photo and Radiation Induced Reactions of Melatonin by Laser Photolysis and Pulse Radioloysis | 369 |
Melatonin Action on Neuropeptide Induction through ReceptorMediated Mechanisms in the Brain | 387 |
Melatonin Receptors in Neuroendocrine Development | 401 |
The Effects of Exogenous Melatonin on the Morphology of Thyrocytes in Pinealectomized and Irradiated Rats | 413 |
The Control of MT Release from Mammalian and Avian Pineal Glands | 425 |
Effect of Chronic Melatonin Administration on Various Physiological Parameters from Old Wistar Rats | 457 |
Melatonin and Sleep in ShiftWorkers | 615 |
Role of Melatonin in the Regulation of Human Circadian Rhythms and Sleep | 633 |
Ramelteon a Selective MT1MT2 Receptor Agonist Provides a Novel Treatment for Insomnia | 647 |
Melatonin Dopamine and Circadian Rhythm in the Restless Legs Syndrome | 669 |
Sleep and Circadian Neuroendocrine Dysregulation in Seasonal Affective Disorder | 681 |
Involvement of Free Radicals and Reactive Oxygen Species in Physiological and Pathological Processes in the Thyroid Gland A Potential Role of Mel... | 699 |
Role of Melatonin in Health and Diseases Headache Disorders | 717 |
Ambient Illumination and Melatonin in the Natural Setting | 731 |
Melatonin Effect on Smooth Muscle and Clinical Utility | 753 |
Melatonin and Woman | 759 |
Effects of Melatonin on the Cardiovascular System | 771 |
Melatonin and Cerebrovascular Disease | 785 |
Melatonin in Focal Cerebral IschaemiaEvidence for Efficacy and Priorities for Future Research | 803 |
Understanding the Role of Melatonin in Epilepsy From Bench to Bedside | 813 |
Role of Melatonin on Alzheimers Disease | 827 |
Longitudinal Measurements of Melatonin Secretion in the Elderly Implications for Alzheimers Disease | 841 |
Interactions of Melatonin with Environmental Factors | 849 |
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Häufige Begriffe und Wortgruppen
AA-NAT acid activity aMT6s antioxidant apoptosis Arendt binding Biochem biological Brain Res breast cancer Bubenik calmodulin Cardinali cells chicken circadian clock circadian rhythms Clin clinical concentrations cycle decrease doses effects of melatonin Endocrinol endogenous enzymes estrogen exogenous melatonin expression Figure free radicals function gene GnIH hamster hormone human hyperhomocysteinemia immune increase induced inhibition interaction ischemia Lett light mammalian mechanisms melatonin administration melatonin levels melatonin receptor melatonin rhythm melatonin secretion melatonin synthesis melatonin treatment metabolism mitochondria mitochondrial modulation molecular mRNA neurons Neurosci night nitric oxide nocturnal onset oxidative stress pathway patients peptide Pharmacol phase photoperiod Physiol physiological pineal gland Pineal Res pinealocytes plasma melatonin protein ramelteon rat pineal gland regulation Reiter RJ release response retina retinal role of melatonin scavenger seasonal seasonal affective disorder serotonin shift-workers signal sleep species stimulation studies suprachiasmatic suprachiasmatic nucleus syndrome therapy thyroid tissues tumors vitro