Handbook on the Toxicology of Metals

Első borító
Monica Nordberg, Gunnar F. Nordberg, Bruce A. Fowler, Lars Friberg
Elsevier, 2011. ápr. 28. - 1024 oldal
Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds.

* Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter
* New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more
 

Tartalomjegyzék

IntroductionGeneral Considerations and International Perspectives
1
General Chemistry Sampling Analytical Methods and Speciation
11
Routes of Exposure Dose and Metabolism of Metals
39
Biological Monitoring and Biomarkers
65
Selected Molecular Mechanisms of Metal Toxicity and Carcinogenicity
79
General Considerations of DoseEffect and DoseResponse Relationships
101
Interactions in Metal Toxicology
117
Epidemiological Methods for Assessing DoseResponse and DoseEffect Relationships
147
Copper
529
Gallium and Semiconductor Compounds
547
Germanium
557
Indium
569
Iron
577
Lead
599
Manganese
645
Mercury
675

Essential Metals Assessing Risks from Deficiency and Toxicity
163
Carcinogenicity of Metal Compounds
177
Immunotoxicology of Metals
197
Reproductive and Developmental Toxicity of Metals
213
Ecotoxicology of MetalsSourcesTransport and Effects in the Ecosystem
251
Risk Assessment
281
Diagnosis and Treatment of Metal PoisoningGeneral Aspects
303
Principles for Prevention of the Toxic Effects of Metals
319
Aluminum
339
Antimony
353
Arsenic
367
Barium
407
Beryllium
415
Bismuth
433
Cadmium
445
Chromium
487
Cobalt
511
Molybdenum
731
Nickel
743
Palladium
759
Platinum
769
Selenium
783
Silver
809
Tellurium
815
Thallium
827
Tin
839
Titanium
861
Tungsten
871
Uranium
881
Vanadium
905
Zinc
925
Index
949
Copyright

Más kiadások - Összes megtekintése

Gyakori szavak és kifejezések

A szerzőről (2011)

Dr Monica Nordberg, Ph.D. is an emerita Professor at Karolinska Institutet (KI), Institute of Environmental Medicine, Stockholm, Sweden. She has served as chair of the Department of Environmental Hygiene, as member, Karolinska Institutet Study Program for Community Medicine, member of Education Policy Committee for Toxicology and Public Health, KI, Stockholm for many years. She has published 175 scientific articles, book chapters and review articles dealing with biochemical mechanisms and health effects related to exposure to metals mainly cadmium, lead and mercury and interaction with selenium. She is one of the editors of a Textbook in Swedish “Arbets- och Miljömedicin, latest (3:rd) Edition 2010. Monica Nordberg is a co- editor and author, of the Handbook on the Toxicology of Metals 3rd edition, Academic Press/Elsevier, 2007 and, for the new 4th edition 2015. This work is within the framework of Scientific Committee on the Toxicology of Metals under International Commission on Occupational Health (SCTM/ICOH) which she served as secretary, chair and presently as former chair. She served as titular member of the Chemistry and Human Health of International Union of Pure and Applied Chemistry issuing recommendations regarding definitions and concepts. She was the Swedish representative in the Management Committee of COST Action, member EU Strategy Environment and Health, SCALE, Technical Working Group Indicators and Priority Diseases. She has experience as an expert serving Japan Food Safety Agency, US Environmental Protection Agency, National Institute for Environmental Health Studies (NIEHS), Agency for Toxic Substances and Disease Registry (ATSDR) USA, World Health Organization HQ, Geneva/International Program on Chemical Safety. Monica Nordberg is a full member of different societies such as Society of Toxicology, USA.

Dr Gunnar F. Nordberg, MD, PhD, is an emeritus Professor at Umea University, Umea, Sweden, where he served as chairman of the Department of Environmental and Occupational Medicine for many years. He has also worked as a scientist at the International Agency for Research on Cancer, Lyon, France and as a Professor and chairman at the Department of Environmental Medicine, Odense University, Denmark. He has published more than 270 papers in Scientific Journals and International Handbooks. In addition, he edited or co-edited 23 Scientific Books and participated in International Task Groups evaluating Risks of Environmental Agents which resulted in 25 international books. Some of these publications resulted from his activities as a chairman of the Scientific Committee on the Toxicology of Metals, International Commission on Occupational Health. He is presently the Task Group Chairman of Cadmium Risk Assessment in the Toxicology and Risk Assessment Group of the International Union of Pure and Applied Chemistry. His Scientific Publications are mainly on Toxicology and Epidemiology of environmental agents, particularly metals. He has coordinated EU- projects on Environmental Epidemiology and Toxicology of Metals and participated as an active scientist in several such projects. He has been the principal investigator of many research projects funded by Swedish funding Agencies and is presently actively involved in such research. He is one of the editors of a Textbook in Swedish “Arbets- och Miljömedicin, latest (3rd) Edition 2010. Chief Editor, Handbook on the Toxicology of Metals, 3rd Ed, published 2007 by Academic Press/Elsevier, new 4th edition publishing October 2014. He has extensive experience as an expert serving Swedish and International Authorities such as the Swedish National Board of Health (Socialstyrelsen), Japan Food Safety Agency, US Environmental Protection Agency, National Institute for Environmental Health Studies (NIEHS), Agency for Toxic Substances and Disease Registry (ATSDR) USA, World Health Organization HQ, Geneva/International Program on Chemical Safety; International Agency for Research on Cancer IARC, Lyon, France, World Health Organization, Europe/European Environment Agency, Copenhagen; European Food Safety Authority (EFSA), Parma, Italy.

Dr. Bruce A. Fowler Ph.D., A.T.S is currently a consultant and an Adjunct Professor at Emory University in Atlanta, Georgia, and a Presidents Professor of Biomedical Research at the University of Alaska- Fairbanks. He has previously held positions as a Senior Fellow/Expert Consultant at ICF International, Associate Director for Science in the Division of Toxicology and Environmental Medicine at ATSDR, Director of the System-wide Program in Toxicology at the University of Maryland and Senior Scientist at the NIEHS. He has been previously selected as a Fellow of the Japanese Society for the Promotion of Science (JSPS), Fulbright Scholar and Swedish Medical Research Council Visiting Professor at the Karolinska Institute in Stockholm Sweden. He has chaired and served on a number of national / international committees in the area of metal toxicology including those of the National Academies of Science, WHO, IARC, National Institutes of Health, and USEPA. Dr. Fowler is the author of over 260 research papers and book chapters dealing with molecular mechanisms of metal toxicity and molecular biomarkers for early detection of metal-induced cell injury. He has been the editor or co-editor of 7 books or monographs on metal toxicology, mechanisms of chemical - induced cell injury and computational toxicology. His current research is focused on computational toxicology and the application of molecular biomarkers for risk assessments of chemical mixtures involving metals, particularly in relation to binary semiconductor materials such as gallium arsenide, indium arsenide as well as lead, cadmium, and arsenic mixtures. He has received a number of awards for his research including a Society of Toxicology Colgate-Palmolive Visiting Professorship in In Vitro Toxicology to the University of Washington and CDC National Center for Environmental Health/ATSDR awards including the Honor Award for Excellence in Quantitative Sciences- Cadmium PbPK Modeling Group Award, NCEH/ATSDR Honor Award for Excellence in Emergency Response Deepwater Horizon Oil Spill Response Team (Domestic) Group Award. As a member of the elemental impurities panel, Dr. Fowler has also received the 2014 USP Award for an Innovative Response to Public Health Challenges (Group Award). He serves on the editorial boards of a number of scientific journals in toxicology and is currently an Associate Editor of Environmental Health Perspectives and Toxicology and Applied Pharmacology.

Bibliográfiai információk